Gunnar Hansson

Professor, University of Gothenburg

CURRICULUM VITAE Gunnar C. Hansson Date of birth: January 30, 1951 in Lessebo, Sweden Swedish personal number: 510130-2791. US social security number: 579-06-5176 Address: Stenungsundsgatan 8 416 74 Gothenburg SWEDEN Address work: Göteborg University Department of Medical Biochemistry Medicinaregatan 9 S-413 90 Gothenburg SWEDEN Social: Married, 3 children (1979, 1982, 1990) Basic education: Studentexamen Växjö (natural sciences) 1970 Medical education: Medical School, University of Gothenburg 1970 1976 Medicine kandidat 1972 M.D. (läkarexamen) 1976 Medical licence Licence to practice medicine in Sweden (legitimerad läkare) 1989 - Scientific training: Part time 1972 1976 Full time 1976 1981 -PhD. (medicine doktorsexamen) 1981 -Docent in Medical and Physiological Chemistry (Medical Biochemistry) 1983 Scientific positions: -Post-doc. position (forskarassistent) 1984-1987 at the Department of Medical Biochemistry -Associate professor (Senior Lecturer for Research) of Molecular Biology at the Medical Faculty of Göteborg University, 1987-1996. Permanent-tenured position (universitetslektor). Professorships -Appointed as Associate Professor (‘Biträdande professor’) in Molecular Biology Göteborg University, 1996-1998 -Full professor of Medical Biochemistry (medicinsk och fysiologisk kemi), Department of Medical Biochemistry, Göteborg University, 1998 - present. Affiliated to Internal Medicine, Sahlgrens Hospital, 20%, 2005- Abroad: -Visiting fellow Feb.1983-June 1984, National Institute of Health, Bethesda, MD., USA -Visiting scientist Mayo Clinic; Scottsdale, Arizona, USA (Sept. 1998-June 1999). Positions as physician: Physician in chronic illnesses clinic (1 month), ear-nose-throat clinic (3 months), paediatrics (university clinic)(3 months), blood bank (3 months), and psychiatry (University clinic)(3 months). Surgery and Internal Medicine at Sahlgrenska Univeristy Hospital (10 months) and emergency room at out-patient clinic in Stenungsund (total about 10 month full time work). Honorary positions: Started PhD-student organisation at Medical Students Union in Göteborg. Its first chairman (ombudsman) 1979-1980. 1981 its secretary. Member of one of the Medical faculty committees (biochemistry) evaluating Ph.D. examinations, 1992-1998. Chairman of the committee 1994-1998. Expert for the Medical faculty in an advisary University committee (HSGU) analysing incorporation of the College for Nursing etc. 1997-1998. Did not support the proposals that came from the main committee. Regular member of the Medical faculty board for basic education (grundutbildningsnämnd) 1997-1998. Vice Chairman of Department of Medical Biochemistry 2000 - 2005 Head of Ph.D. student education 2000 - 2006. Board member of Centre for Gastroenterological Research, Göteborg University 1998 - 2005 Repsonisble for space allocation within the Department, 2000 - present. Chairman of Science committee of Department 2006 -. Board member of The Swedish Society for Biochemistry and Molecular Biology 2004 - present. Board member of The Swedish Society for Mass Spectrometry (SMSS) 1997 - 2006 Chairman of The Swedish Society for Mass Spectrometry (SMSS) 2006 - Board member of MIVAC (Mucosa, immunobiology, and vaccine center) 2006- Member of the board for Sahlgrenska Academy (Faculty borad for Medical -, Dental -, and Nursery School) at Göteborg University, 2007 - Teaching: Long experience of teaching at undergraduate (Medical school, Dental school, Pharmacy school) as well as several Ph. D. courses. Large experience in teaching administration. Present comittments: • Head (blockchef) for the Molecular Cell Biology part (25 weeks) of the Pharmacy (Apotekar) program, 2000 - present. • Planned and responsible (kursledare) for the detailed planning of Molecular Cell Biology part 4, Metabolism (5 weeks) of the Pharmacy (Apotekar) program, 2007 - . • Planned and responsible (kursledare) for a practical course in modern cell biology at advanced level for Biopharmact students (BVLP, Apotekar), 5 credit points, 2000-2007, 2010-. • Teaching biochemistry of the gastrointestinal canal for medical students, 1 week, 1995- Bibliography: See separate list. Published 170 scientific publications. 29 of these have been published in The Journal of Biological Chemistry. Three recent in Proc. Natl. Acad. Sci. USA Selected invitation to conferences/presentations (last 5 years only): 2004: ELSO Cell biology meeting, Nice, France Invited lecture at Stanford University, USA Invited lecture at McGill University, Canada 2005: Gordon conference: Cilia, mucus and mucociliary clearance, USA European CF Conference, Greece Conference: Mucin in Health and Disease, England 2006: Symposium: Frontiers in Glycomics: Bioinformatics and biomarkers in disease, NIH, Bethesda, MD Symposium: Pathobiology of the intestinal mucosa, Hannover Invited lectures at Univ. North Carolina, Chapel Hill, NC. Invited lecture at ETH, Zurich, Switzerland 2007: Cystic Fibrosis Conference, Willamsburg, May 2007 13th International Congress of Immunology August 2007, Rio de Janeiro, Brazil Mucin in Health and Disease, Cambridge, July 2007 Tear Fluid Symposium, Sicily, Sept. 2007 North American CF Conference, Anaheim, CA. Symposium organizer and speaker, October 2007 2008: Conference on innate immunity, MTC, KI, Jan. 2008 European Cystic Fibrosis Conference, Prague, June 2008 6th European Mucosal Immunology Group meeting “EMIG 2008” Milan, Italy, 2008. Ph. D. course in Copenhagen (October) Ph. D. course Helsinki (December) 2009 (until now) Cilia, mucus and mucociliary interactions, Gordon Confererence, Italy, Feb 2009 Dutch Gastroenterological Society, The Netherlands March 2009 Cystic Fibrosis Foundation, Jubilee, Stockhom April 2009 Mucus in Health and Disease, Cambridge, July 2009 Microbes and Health, National Acad. Sci. USA Sackler Symposia, CA, Nov. 2009 Organisation of international meetings: Mucus and mucins, Gothenburg 1995. About 150 participants. Mass spectrometry in biology, Hindås 1997. About 50 participants. XIIIth Interantional Cystic Fibrosis Congress, Stockholm 2000, About 1500 participants Innate immunity in the gastrointestinal tract, October 2003, About 90 participants CFTR in the gastrointestinal tract, November 2005, About 90 participants Symposium at North American Cystic Fibrosis Conference, October 2007 Posttranslational modifications, Annual SMSS symposium, April 2008, About 100 paricipants Annual scientific meeting for SMSS, 2007, 2008, 2009 Vice-chairman for FEBS 2010, joint meeting organized by Sweden-Norway in Gothenburg Organisation of seminar series Together with Per Elias organised the seminar series 'Molecular Aspects on Cell Biology' 1991-1998. Science Policy Article on funding of medical research in Dagens Nyheter, main Swedish newspaper, 2001 Editorial Board Biochemical Journal 2003 - Glycobiology 2006 - Reviewer for the following journals: Biochemical Journal (member of advisary board) Biotechnology & Applied Biochemistry British Journal of Cancer EMBO Journal EMBO Reports European Journal of Biochemistry European Journal of Cancer European Journal of Cell Biology European Respiratory Journal FASEB Journal FEBS letters Gastroenterology Glycobiology Glycoconjugate Journal Gut International Journal of Cancer J. Cellular Biochemistry Lipids The Journal of Biological Chemistry (JBC) Tumor Biology Evaluation of applications: The Swedish Cystic Fibrosis Foundation, 1998 - EU FP6, several Welcome trust, UK Israel Science Foundation German CF Foundation UK CF Foundation Canadian CF Foundation Austrian Science Foundation Professor in Biochemistry, SLU Uppsala, 2002 Lektor in Analytical Chemistry, Uppsala 2004 Lektor Copenhagen University 2008 Current major external funding:  Science Research Council 2007-2009; SEK 1 200 000/year; Structure, function and biosynthesis of mucins from the intestinal tract.This application got the highest score (18.8 ) given that year by the Biochemistry Committee.  Science Research Council 2009-2011; SEK 2 000 000/year; Samverkansprojekt.  The Swedish Cancer Foundation 2009-2011; SEK 850 000/year; Tumor-assocoaited mucins and their role in the development of cancer  Wallenberg Foundation, 2007 Expensive equipment, SEK 5 000 000: Mass Spectrometer - Orbitrap  EU financed project 2007-2010 Proteases in inflammatory bowel diseases, 800 000/year  LUA/ALF, Ulcerative Colitis - a disease of the mucosal barrier, 2008-2010, 1 700 000/year  Lundberg Foundation 2008, 1 300 000 for equipment Supervision of PhD.- completed thesis (year of graduation and current position) 1. Dan Baeckström 1995, his own group at the Dept. Medical Biochemistry in Gothenburg 2. Jing-Yang Mu, 1996, together with prof. Ove Lundgren 3. Ke Zhang, 1997, bioinformatic scientist at a biotech company; Ceres Inc., CA, USA (http://www.ceres-inc.com/). 4. Niclas Karlsson, 1997, Senior Scientist Centre for BioAnalytical Sciences, Chemistry Department, NUI Galway, Ireland 5. Rein Sikut, January 30, 1998, head of immunology group at a biotech. company; Finnish Immuntechnology Ltd., Tartu, Estonia (http://www.finnish-immunotech.com/) 6. Noomi Asker, May 27, 1998. Post-doc Physiology 7. Magnus Axelsson, April 23, 1999, Internship in Clinical Pharmacology 8. Kristina Thomsson, May 2000, post-doc in my laboratory. 9. Fredrik Olson, October 2002. post-doc Wallenberglaboratoriet, Götebrog University 10. Christian Andersson 2003, post-doc in another laboratory, Göteborg University 11. Sirle Laos Dec. 2005, post-doc Barcelona, Spain 12. Martin Lidell Mar. 2006, post-doc at Inst. Biomedicine, Göteborg University 13. Emily Malmberg, Sept 2006, Post-doc Copenhagen University 14. Jessica Holmén Larsson, October 2006, post-doc at MIVAC 15. Tiange Lang, October 2007, post-doc in France 16. Malin Johansson, June 2009, post-doc in the lab. Currently supervising four Ph.D. students. Former and current international and national Post-docs in the laboratory: 1.Daniella Steel (from UK), currently scientist at Chalmers, Göteborg 2. Rein Sikut (from Estonia), see above 3. Klaus Godl (from Germany), starting as a protemics expert at a biotech. company; Axxima, Munchen, Germany (http://www.axxima.com/) 4. Julia Fernandez-Rodrigues (from Spain), at Swegene imaging centre 5. Cristina Weinberg (from New Zealand), BioTech company in New Zealand 6. Malin Bäckström (from Sweden), in my laboratory 7. Elin Grahn (from Sweden), post-doc in Örebro 8. Kristina Thomsson, in my laboratory 10. Iris Härd, at the Dept. 11. Jenny McKinzie, Shared post-doc with Univ. Oslo, structural project 11. Ana Rodriguez Pinero, Spain, in my laboratory 12. Daniel Ambort, Switzerland, in my laboratory 13. Babu Sharamsha, India, in my laboratory 14. Malin Johansson, in my laboratory. Current staff in the laboratory Four Ph.D. students Six post-docs (one works in Oslo) One senior scientist, mass spectrometrist (Ph.D.) One technician One nurse (part-time) External PhD. examiner 1. Peter Aagaard-Nielsen, 1997, Copenhagen, Denmark 2. Helle Hassan, 1999, Copenhagen, Denmark 3. Torunn Thingstad 2000, Oslo, Norway 4. Hans Wandall, 2004, Copenhagen, Denmark 5. Mads Peter Agervig Tarp, 2006, Copenhagen, Denmark August 2009